Vaccines for the Prevention of Melioidosis and Glanders

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منابع مشابه

Bichat guidelines for the clinical management of glanders and melioidosis and bioterrorism-related glanders and melioidosis.

Glanders and melioidosis are two infectious diseases that are caused by Burkholderia mallei and Burkholderia pseudomallei respectively. Infection may be acquired through direct skin contact with contaminated soil or water. Ingestion of such contaminated water or dust is another way of contamination. Glanders and melioidosis have both been studied for weaponisation in several countries in the pa...

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Recent Progress in Melioidosis and Glanders

B. pseudomallei and B. mallei can survive hostile conditions, becoming resilient to many antimicrobial agents, including antibiotics. In the paper by Rholl et al. (2011), the resistance to β-lactams, such as ceftazidime, was investigated. Genetic analysis of penA gene, encoding a putative twin arginine translocase (TAT)-secreted β-lactamase, demonstrated that PenA is secreted via the TAT system...

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Burkholderia pseudomallei and Burkholderia mallei: Melioidosis and Glanders

The genus Burkholderia is currently composed of many species, but only three are notable pathogens for humans or animals: the former cepacia complex (described in Chapter 220) pseudomallei (the agent of melioidosis), and mallei (the agent of equine glanders). All three are aerobic, nonsporulating, straight or slightly curved gram-negative bacilli that were formerly placed in the genus Pseudomonas.

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15 صفحه اول

Development of capsular polysaccharide-based glycoconjugates for immunization against melioidosis and glanders

Burkholderia pseudomallei and Burkholderia mallei, the etiologic agents of melioidosis and glanders, respectively, cause severe disease in humans and animals and are considered potential agents of biological warfare and terrorism. Diagnosis and treatment of infections caused by these pathogens can be challenging and, in the absence of chemotherapeutic intervention, acute disease is frequently f...

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ژورنال

عنوان ژورنال: Current Tropical Medicine Reports

سال: 2017

ISSN: 2196-3045

DOI: 10.1007/s40475-017-0121-7